Welcome to Griffin Discoveries! |
Griffin Discoveries is a drug discovery company that develops innovative G protein-coupled receptor (GPCR) targeting drugs for therapeutic areas with unmet clinical need. The company spun-out of VU University Amsterdam in 2009 and is based on over 30 years of GPCR research. At present the company works in close collaboration with the academic group and has obtained all intellectual property rights to its GPCR research programs. |
| Services
We offer services to the biotech and pharmaceutical industry ranging from compound profiling against our panel of unique histamine receptors to GPCR assay development, to medicinal chemistry programs. Our approach is flexible and tailored to customer needs. Different arrangements are possible where we work either on a fee-for-service basis or FTE funded collaboration. |
Research and Development
Our company develops a portfolio of small molecule drugs that target histaminergic G protein-coupled receptors in a therapeutic area of unmet clinical demand. Current in-house discovery is comprised of a selective histamine H4R antagonist and histamine H4R/H1R antagonist program. In addition to these programs, several chemotypes have been identified that allow the development of compounds with mixed profiles including dual-action H3R/H4R ligands. |
